Journal articles and preprints
A.R.C. Avecilla, J. Thomas, and F. García Quiroz. Genetically-encoded phase separation sensors for intracellular probing of biomolecular condensates. bioRxiv [PrePrint]. 2024 August. doi: https://doi.org/10.1101/2024.08.29.610365. (link)
M.C. Giraldo-Castaño, K.A. Littlejohn, A.R.C Avecilla., N. Barrera-Villamizar, and F. García Quiroz. Programmability and biomedical utility of intrinsically-disordered protein polymers. Advanced Drug Delivery Reviews, 115418, 2024 (link).
K.P Kubelick and F. García Quiroz. Biocondensates fuel tumor immune evasion. Nature Cancer (2023). (link)
A.R.C. Avecilla and F. García Quiroz. Cracking the skin barrier: liquid-liquid phase separation shines under the skin. JID Innovations, 1:100036, 2021. (link)
K. Laaß, F. García Quiroz, J. Hunold, S. Roberts, A. Chilkoti, D. Hinderberger. Nanoscopic dynamics dictate the phase separation behavior of intrinsically disordered proteins. Biomacromolecules, 22:1015-1025, 2021. (link)
F. García Quiroz, V. Fiore, J. Levorse, L. Polak, E. Wong, H. Amalia Pasolli, E. Fuchs. Liquid-liquid phase separation drives skin barrier formation. Science, 367, eaax9554, 2020. (link) (related Perspective article in Science)
V.F. Fiore, M. Krajnc, F. Garcia Quiroz, J. Levorse, H.A. Pasolli, S.Y. Shvartsman, E. Fuchs. Mechanics of a multilayer epithelium instruct tumor architecture and function. Nature, 585:433-439, 2020. (link) (related Perspective article in Nature)
F. García Quiroz, N. Li, S. Roberts, P. Weber, M. Dzuricky, Y.G. Yingling, A. Chilkoti. Intrinsically disordered proteins access a range of hysteretic phase separation behaviors. Science Advances, 5, eaax5177, 2019. (link)
N. Li, S. Roberts, F. García Quiroz, A. Chilkoti, Y. Yingling Sequence Directionality Dramatically Affects LCST Behavior of Elastin-Like Polypeptides. Biomacromolecules, 9:2496-2505, 2018. (link)
I. Weitzhandler, M. Dzuricky, I. Hoffmann, F. Garcia Quiroz, M. Gradzielski, A. Chilkoti. Micellar self-assembly of recombinant resilin-like/elastin-like block copolypeptides. Biomacromolecules, 18:2419-2426, 2017. (link)
F. García Quiroz, A. Chilkoti. Sequence heuristics to encode phase behaviour in intrinsically disordered protein polymers. Nature Materials, 14:1164-1171, 2015. (link) (related Perspective article in Nature Materials) (Covered by Science Magazine)
N. Li, F. García Quiroz, C. Hall, A. Chilkoti, Y. Yingling. Molecular description of the LCST behavior of an elastin-like polypeptide. Biomacromolecules, 15:3522–3530, 2014. (link)
W. Liu, J.R. McDaniel, X. Li, D. Asai, F. Garcia Quiroz, J. Schaal, J.S. Park, M. Zalutsky, A Chilkoti. Brachytherapy using injectable seeds that are self-assembled from genetically encoded polypeptides in situ. Cancer Research, 15:5956-5965, 2012. (link)
D. Asai, D. Xu, W. Liu, F. Garcia Quiroz, D.J. Callahan, M.R. Zalutsky, S.L. Craig, A. Chilkoti. Protein polymer hydrogels by in situ, rapid and reversible self-gelation. Biomaterials, 33:5451-5458, 2012. (link)
N. Higuita-Castro, D. Gallego-Perez, A. Pelaez-Vargas, F. García Quiroz, O.M. Posad, LE. López, C.A. Sarassa, P. Agudelo-Florez, F.J. Monteiro, A.S. Litsky, D.J. Hansford. Reinforced portland cement porous scaffolds for load- bearing bone tissue engineering applications. J Biomed Mater Res B Appl Biomater, 100B:501-507, 2012. (link)
M. Amiram*, F. García Quiroz*, D. Callahan, A. Chilkoti. A Highly Parallel Method for Synthesizing DNA Repeats Enables the Discovery of ‘Smart’ Protein Polymers. Nature Materials, 10:141–148, 2011. *Co-first authors (Related Pespective article in Nature Materials)
D. Gallego, N. Higuita, F. García Quiroz, O.M. Posada, L.E. López, A.S. Litsky, D.J. Hansford. Portland cement for bone tissue engineering: effects of processing and metakaolin blends. J Biomed Mater Res B Appl Biomater, 98B: 305-315, 2011. (link)
F. García Quiroz, O.M. Posada, D. Gallego, N. Higuita., P. Agudelo, C. Sarassa, D. Hansford, L.E. López. Housekeeping gene stability influences the quantification of osteogenic markers during stem cell differentiation to the osteogenic lineage. Cytotechnology, 62:109-120, 2010. (link)
(13) J.R. McDaniel, J.A. Mackay, F. García Quiroz, A. Chilkoti. Recursive Directional Ligation by Plasmid Reconstruction Allows Rapid and Seamless Cloning of Oligomeric Genes. Biomacromolecules, 11:944-952, 2010. (link)
R. Capone, F. Garcia Quiroz, P. Prangkio, I. Saluja, A.M. Sauer, M. R. Bautista, R.S. Turner, J. Yang, M. Mayer. Amyloid-β-induced ion flux in artificial lipid bilayers and neuronal cells: Resolving a controversy. Neurotoxicity Research, 16:1-13, 2009. (link)
(15) F. García Quiroz, O.M. Posada, D. Gallego, N. Higuita., P. Agudelo, C. Sarassa, D. Hansford, L.E. López. Isolation of human bone marrow mesenchymal stem cells and evaluation of their osteogenic potential. Revista Ingeniería Biomédica, 3: 48-55, 2008. (link)
D. Gallego, N. Higuita, F. García, N. Ferrell, D. Hansford. Bioactive coatings on Portland cement substrates: Surface precipitation of Apatite-like crystals. Materials Science and Engineering C, 28(3): 347-352, 2008. (link)
Book chapters
F. García Quiroz, A. Chilkoti. The Language of protein polymers. In Sequence-Controlled Polymers: Synthesis, Self-Assembly, and Properties; Lutz, et al.; ACS Symposium Series; American Chemical Society: 2014, pages 15-33. (link)
Roberts, S. Costa, J. Schaal, J.R. Simon, M. Dzuricky, F. Garcia Quiroz, A. Chilkoti. Elastin-Like Polypeptides. In Comprehensive Biomaterials (Second Edition), edited by Paul Ducheyne, Elsevier: 2017, Pages 90-108. (link)
Patents
F. Garcia Quiroz, E. Fuchs. Phase separation sensors and uses thereof. U.S. Patent App. No. 20230061804A1, March 2, 2023. (link)
G.P. Lopez, A. Chilkoti, A. Ghoorchian, F. García Quiroz. Systems and devices for protease detection based on engineered polymers and biopolymers and methods of use. US Patent No. 11,268,127, March 8, 2022. (link)
A. Chilkoti, F. García Quiroz, M. Amiram. Phase transition biopolymers and methods of use. US Patent No. 9,771,396, Sept 26, 2017. (link) [Licensed]
A. Chilkoti, F. García Quiroz, M. Amiram. Phase transition biopolymers and methods of use. US Patent No. 8,470,967, June 25, 2013. (link) [Licensed]
